Taurine/Choline Chloride Deep Eutectic Solvent as a Novel Eco-Compatible Catalyst to Facilitate the Multi-Component Synthesis of Pyrano[2,3-d]Pyrimidinone (Thione), Hexahydroquinoline, and Biscoumarin Derivatives

Abstract

In this study, taurine/choline chloride deep eutectic solvent has been synthesized, characterized and used as an eco-compatible catalyst in the synthesis of pyrano[2,3-d]pyrimidinone (thione), hexahydroquinoline, and biscoumarin derivatives. The significant features of the present method are biodegradability, cost efficiency, easy preparation of the catalyst, short reaction times, production of target compounds in high yields, and simple work-up procedure. Also, the catalyst can be recovered easily and reused for several cycles in the studied reactions.

Keywords:

• Biscoumarins
• choline chloride
• deep eutectic solvent
• hexahydroquinolines
• pyrano[23-d]pyrimidinones
• taurine

Acknowledgments

The authors are thankful to the Research Council of the University of Guilan for the partial support of this research.

Disclosure statement

There are no conflicts of interest.