β‐Cyclodextrin: An Efficient Supramolecular Catalyst for the Synthesis of Pyranoquinolines Derivatives under Ultrasonic Irradiation in Water

Abstract

A newer, convenient and efficient approach has been designed for the diverse synthesis of 2-amino-4H-pyranoquinolines and achieved by a one-pot three-component reaction of aromatic aldehydes with ethyl cyanoacetate/malononitrile and 8-hydroxyquinoline catalyzed by β-cyclodextrin as a reusable supramolecular catalyst in an aqueous medium under ultrasound irradiation. Target products were synthesized in a tandem process, which meets their requirements of pharmaceutical chemistry.

Keywords:

• Multicomponent reaction
• β‐cyclodextrin
• supramolecular catalysis
• ultrasonic irradiation
• pyranoquinolines

Acknowledgments

One of the authors CKJ is very much grateful to the Council of Scientific and Industrial Research (CSIR), New Delhi for the award of a research fellowship. The author is also thankful to the Head, Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad for providing laboratory facility.

Disclosure statement

The authors declare no competing financial interest.

Author contributions

The manuscript was written through the contributions of all authors. All authors have approved the final version of the manuscript.

Additional information

Funding

This article was funded by Council of Scientific and Industrial Research, India.