A Simple and Efficient [(n-Bu₃Sn)₂MO₄]_n Catalyzed Synthesis of Quinazolinones and Dihydroquinazolinones

Abstract

A novel unprecedented approach for the synthesis of various quinazolinones and dihydroquinazolinones has been using [(n-Bu₃Sn)₂MO₄]_n as a catalyst. The reaction has been screened in various solvents and a gram scale experiment has also been demonstrated under given conditions. Further, the substrate scope of the reaction and the recyclability of the catalyst have also been studied.

Graphical Abstract

Keywords:

• [(n-Bu₃Sn)₂MO₄]_n
• dihydroquinazolinone
• quinazolinone
• recyclable catalyst

Acknowledgements

The authors would like to thank Dr. Reddy’s Laboratory, Hyderabad for providing facilities to carry out this work. One of the authors Dr. Krishnaji, acknowledges CHRIST (Deemed to be University), Bangalore for funding Major Research Project (MRP # MRPDSC-1723).