Preparation Immobilized Cu Nanoparticles on Modified Metal-Organic Framework via Linker Design as an Effective and Highly Efficient Nanocatalyst for the Synthesis of Propargyl Amines Derivatives

Abstract

TMU-16-NH₂ metal-organic framework was modified with glyoxal ligand via post-synthetic process, and the new support was applied for the immobilization of uniform Cu nanoparticles (NPs). These Cu NPs on MOF support with 1.2 mol% loading was used as highly efficient heterogeneous catalyst for the synthesis of propargyl amines via a three‐component reaction of amines, aldehydes, and alkynes (A³-coupling) under N₂ atmosphere and solvent-free condition. In addition, this catalyst using simple separation could be recycled and reused for five consecutive cycles without appreciable loss in performance. The structure of the Cu@TMU-16-NH₂-Gl was mainly maintained after reaction and also catalytic activity and stability were still high. Our strategy also efforts to develop an appropriate, simple, cost-effective, and green approach for organic reaction.

Keywords:

• Metal-organic frameworks
• Post-synthetic modification
• Nanocatalyst
• A³-coupling reaction
• heterogeneous catalyst

Acknowledgments

We would like to thank the University of Mazandaran for financial support (Research Council Grant).