Synthesis of 4,4'-(Aryl Methylene)Bis(3-Methyl-1H-Pyrazol-5-ol) Derivatives and Pyrano[2, 3-c] Pyrazole Derivatives Using an Engineered Copper-Based Nano-Magnetic Catalyst (Fe₃O₄@SiO₂/Si(OEt)(CH₂)₃NH/CC/EDA/Cu(OAc)₂)

Abstract

In this work, Fe₃O₄@SiO₂/Si(OEt)(CH₂)₃NH/CC/EDA/Cu(OAc)₂ as a copper-based nano-magnetic catalyst was prepared and characterized by Energy Dispersive X-ray analysis (EDX) and EDX-Mapping, Field-Emission Scanning Electron Microscopy (FESEM), Transmission Electron Microscopy (TEM), Vibrating Sample Magnetometer (VSM), Fourier transform infrared spectroscopy (FT-IR), Thermal Gravimetric Analysis (TGA) and Differential Thermal Analysis (DTA). The catalytic activity of the synthesized catalyst was investigated in the synthesis of 4,4'-(aryl methylene)bis(3-methyl-1H-pyrazol-5-ol)s and pyrano[2,3-c]pyrazoles by the one-pot reactions under solvent-free conditions. Short reaction times, high yields and solvent-free conditions are some benefits of the presented work.

Graphical Abstract

Keywords:

• Nano Fe₃O₄
• solvent-free reaction
• multi-component reaction
• 4
• 4'-(Aryl methylene)bis(3-methyl-1H-pyrazol-5-ol) and Pyrano[2,3-c]pyrazole

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The authors would like to appreciate the Research Council of Bu Ali Sina University for providing the facilities and financial support of this research.