Abstract
A simple, new, and cost-efficient alternative route has been designed for the synthesis of unique β-amino alcohols under metal-free condition from new type of 1,2- disubstituted styrene epoxides obtained from substituted p-hydroxycinnamic acids via greener approach. It was followed by density functional theory (DFT) based computational study to investigate the mechanistic path for generating acetylated amino alcohols i.e. the main key step for the formation of β-amino alcohols.
Graphical Abstract
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Disclosure statement
No potential conflict of interest was reported by the authors.