Fe₃O₄@SP@Chitosan@Fe₃O₄ Nanocomposite: A Catalyst with Double Magnetite Parts for Sustainable Synthesis of Novel Azo-Linked 4-Benzylidene-2-Phenyloxazol-5-Ones

Abstract

Chitosan‐functionalized silica‐double magnetite parts that contains magnetite in the core and outer layer of synthetic nanoparticles (Fe₃O₄@SP@chitosan@Fe₃O₄) were prepared and approved by field emission scanning electron microscope (FE-SEM), fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), X-ray powder diffraction (XRD), X-ray spectroscopy (EDS), transmission electron microscope (TEM), and vibrating sample magnetometry (VSM). The presence of Fe₃O₄ in the outer shell of the synthetic nanoparticle, in addition to its core, increased the acidity and other properties of the nanoparticle or composite. This structural modification increased the reusability up to eight cycles due to the improvement of magnetic properties, and on the other hands, the reaction time and yields were improved. Fe₃O₄@SP@chitosan@Fe₃O₄ nanoparticle supply an eco-friendly procedure for the synthesis of some novel 4-benzylidene-2-phenyloxazol-5-ones through one-pot reaction of various benzoyl chlorides, glycine and synthetized azo-linked benzaldehydes. These high-yield compounds were obtained at short reaction times. The structures of the synthesized 4-benzylidene-2-phenyloxazol-5-ones were confirmed by FT-IR spectroscopy, and ¹H and ¹³C NMR data, and elemental analyses.

Graphical Abstract

Key Words:

• Azo dye
• magnetic nano-catalyst
• 4-benzylidene
• oxazole
• Fe₃O₄@SP@chitosan@Fe₃O₄

Disclosure statement

There is no conflict of interest.

Additional information

Funding

Financial support by Rasht Branch, Islamic Azad University is gratefully acknowledged.