Therapeutic Efficacy of Benzimidazole and Its Analogs: An Update

Abstract

Benzimidazoles, one of the nitrogen heterocycles, possess pharmaceutical and biological potential. This heterocycle has been known for pharmacological activities such as antifungal, antibacterial, and antiparasitic. The reports on the activities of the compounds containing this basic moiety are well-reported in the literature, specifically as anthelmintic and proton pump inhibitors. This review covers the synthesis of benzimidazole analogs by feasible methods from our laboratory. Also, the present review explores the recent reports on benzimidazole analogs designed as antibacterial, antifungal, anticancer, and antiviral agents.

Graphical Abstract

Keywords:

• Benzimidazole
• medicinal drugs
• antibacterial
• antifungal
• anticancer and antiviral activity

Acknowledgment

Author is thankful to college management for their constant encouragement to complete this review article.

Disclosure statement

No potential conflict of interest was reported by the author(s).