A Facile, One-pot, and Green Method for Synthesis of 2-Aryl-3-(Phenylamino)Dihydroquinazolin-4(1H)-One Derivatives Using Sodium Lauryl Sulfate (SLS) in Aqueous Media at the Room Temperature

Sara Moghadam Farida Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IranView further author information

Ali Moazzama Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IranView further author information

Keyvan Pedrooda Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IranView further author information

Yahya Dashtib Science and Research Branch, Islamic Azad University, Tehran, IranView further author information

Samanesadat Hosseinic Shahid Beheshti University of Medical Sciences, Tehran, IranView further author information

Bagher Larijania Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IranView further author information

Mohammad Mahdavia Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IranCorrespondence[email protected]
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Abstract

A facile, one-pot, and green method for synthesis of 2-aryl-3-(phenylamino)dihydroquinazolin-4(1H)-one derivatives using Sodium Lauryl Sulfate (SLS) in aqueous media at room temperature through a reaction between isatoic anhydride, phenylhydrazine, benzaldehyde derivatives in the presence of SLS. This one-pot protocol provides these valuable desired compounds under mild and green conditions with excellent efficiency by using simple available starting materials.

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No potential conflict of interest was reported by the author(s).

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This work was supported by University of Tehran.

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A Facile, One-pot, and Green Method for Synthesis of 2-Aryl-3-(Phenylamino)Dihydroquinazolin-4(1H)-One Derivatives Using Sodium Lauryl Sulfate (SLS) in Aqueous Media at the Room Temperature

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A Facile, One-pot, and Green Method for Synthesis of 2-Aryl-3-(Phenylamino)Dihydroquinazolin-4(1H)-One Derivatives Using Sodium Lauryl Sulfate (SLS) in Aqueous Media at the Room Temperature

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