Progress in Synthetic Trends Followed for the Development of 1,2,3-Triazole Derivatives: A Review

Abstract

Since the beginning of click chemistry, 1,2,3-triazoles has been at the center of modern organic chemistry. This versatile framework has found broad applications in organic synthesis, drug discovery, chemical biology, polymer chemistry, supramolecular chemistry, bioconjugation, fluorescent imaging, and materials sciences. Due to tremendous use of 1,2,3-triazoles in chemistry, synthesis of this moiety from the easily available chemicals is desirable. This review covers different conventional and non-conventional approaches adopted for the synthesis of 1,2,3-triazole derivatives.

Keywords:

• 1,2,3-Triazoles
• Huisgen reactions
• click chemistry
• 1,3-dipolar cycloaddition
• triazole synthesis

Acknowledgements

The author is thankful to Dr. Mohammad Abid, Department of Biosciences, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi, India for inspiring to write this review article. The author also acknowledges the Department of Chemistry, Government Degree College for Women Baramulla, J&K India, for providing the logistical support throughout the review work.

Disclosure statement

No potential conflict of interest was reported by the author(s).