Activated Fjord-Region Metabolites of Dibenzo[a,l]pyrene: Synthesis and Mutagenic Activities of the Diastereomeric syn− and anti−11,12-Dihydrodiol 13,14-Epoxides

Albrecht Seidel Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131, Mainz, FRG

Andreas Luch Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131, Mainz, FRG

Karl L. Platt Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131, Mainz, FRG

Franz Oesch Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131, Mainz, FRG

Hansruedi Glatt Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131, Mainz, FRG

Abstract

An efficient synthesis and the mutagenicity in Salmonella typhimurium and V79 cells of the diastereomeric syn− and anti−11,12-dihydrodiol 13,14-epoxides of dibenzo[a,l]pyrene are described.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Activated Fjord-Region Metabolites of Dibenzo[a,l]pyrene: Synthesis and Mutagenic Activities of the Diastereomeric syn− and anti−11,12-Dihydrodiol 13,14-Epoxides

Information for

Open access

Opportunities

Help and information

Activated Fjord-Region Metabolites of Dibenzo[a,l]pyrene: Synthesis and Mutagenic Activities of the Diastereomeric syn− and anti−11,12-Dihydrodiol 13,14-Epoxides

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature