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Critical Reviews in Analytical Chemistry Volume 46, 2016 - Issue 3
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Review Articles

Gallic Acid: Review of the Methods of Determination and Quantification

Felipe Hugo Alencar FernandesSchool of Pharmaceutical Sciences, São Paulo State University, Araraquara, BrazilCorrespondence[email protected]
&
Hérida Regina Nunes SalgadoSchool of Pharmaceutical Sciences, São Paulo State University, Araraquara, Brazil
Pages 257-265 | Published online: 27 Apr 2016
 
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ABSTRACT

Gallic acid (3,4,5 trihydroxybenzoic acid) is a secondary metabolite present in most plants. This metabolite is known to exhibit a range of bioactivities including antioxidant, antimicrobial, anti-inflammatory, and anticancer. There are various methods to analyze gallic acid including spectrometry, chromatography, and capillary electrophoresis, among others. They have been developed to identify and quantify this active ingredient in most biological matrices. The aim of this article is to review the available information on analytical methods for gallic acid, as well as presenting the advantages and limitations of each technique.

Funding

The authors acknowledge funding from CNPq (Brasília, Brazil) and CAPES Foundation.

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