Electroanalytical Approaches for Determination of Prostate Cancer Drugs in Biological Samples and Dosage Forms

Abstract

Prostate cancer is the second most common malignant type of cancer in men and fifth among fatal types of cancer. Because drugs used in prostate cancer, such as in many other drugs, are also present in low concentrations in body fluids, it is important to develop highly sensitive and sensitive methods that allow the correct amount of prostate cancer drugs to be determined at low concentrations in biological specimens. Electrochemical approaches for the quantitation of prostate cancer drugs have several advantages over other common techniques, including sensitive, selective, fast, broad linear concentration range. Over the years, various modified working electrodes such as graphite, glassy carbon, carbon paste electrode, carbon composites, and nanotubes have been developed and used in various forms for electroanalytical determinations of prostate cancer drugs. One of the important developments in the electroanalytical chemistry is the surface modification of electrodes. The various sensing strategies for the electrochemical detection techniques such as voltammetry, polarography, amperometry, potentiometry have been used for prostate cancer drugs. This review focuses on studies published over the past years on sensitive and selective detection of prostate cancer drugs in biological fluids and dosage forms using electrochemical methods.

Keywords:

• Drugs
• electrochemistry
• electrodes
• prostate cancer