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Abstract
Conjugated linoleic acid (CLA) consists of a group of positional and geometric conjugated isomers of linoleic acid. Since the identification of CLA as a factor that can inhibit mutagenesis and carcinogenesis, thousands of studies have been conducted in the last several decades. Among the many isomers discovered, cis-9, trans-11 CLA is the most intensively studied because of its multiple, isomer-specific effects in humans and animals. This paper provides an overview of the available data on cis-9, trans-11 CLA, including its isomer-specific effects, biosynthesis, in vivo/in vitro research models, quantification, and the factors influencing its content in ruminant products.
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Funding
This research was supported by Bio-industry Technology Development Program (313002031WT020) for Ministry of Agriculture, Food and Rural Affairs, Republic of Korea. Additionally, this research was supported by Project funded by China Postdoctoral Science Foundation (Project No. 2014M550177) and by Doctoral Project Sponsored by the Scientific Research Foundation of Jilin Agricultural University of China (2014).
