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Original Articles

Antibacterial Activities of Coleus Aromaticus Benth (Lamiaceae) Essential Oil against Oral Pathogens

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Pages 13-17 | Received 01 Jun 2008, Accepted 01 Mar 2009, Published online: 09 Dec 2011
 

Abstract

Leaf essential oil of Coleus aromaticus (Lamiaceae) from Cambodia was steam-distilled and investigated for its percentage composition and antibacterial activity against ffteen oral microflora pathogen strains. The volatile oil sample investigated in this work contained mainly thymol (57.4%), carvacrol (13.5%), γ-terpinene (5.6%), and p-cymene (5.2%).

The in vitro antibacterial experiments revealed that on tested bacteria the minimum inhibitory concentration (MIC) ranged 40–80 µL/Land the minimum bactericidal concentration (MBC) 80–150 µL/L. These findings support the idea that the C. aromaticus essential oil sample tested here could be suitable for use as a natural active ingredient in natural and low-cost drugs against oral microflora.

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