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Original Article

The Complete Coding Region Sequence of River Buffalo (Bubalus bubalis) SRY Gene

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Pages 77-80 | Received 22 Sep 2003, Published online: 11 Jul 2009
 

Abstract

The Y-linked SRY gene is responsible for testis determination in mammals. Mutations in this gene can lead to XY Gonadal Dysgenesis, an abnormal sexual phenotype described in humans, cattle, horses and river buffalo. We report here the complete river buffalo SRY sequence in order to enable the genetic diagnosis of this disease. The SRY sequence was also used to confirm the evolutionary divergence time between cattle and river buffalo 10 million years ago.

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