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Starting with 5-chloro-1,3-diphenyl- 1H-pyrazole-4-carboxaldehyde (1), both of (4-cyano-1,3-diphenyl-1H-pyrazol-5-ylthio) acethydrazide (6) and 1,3-diphenyl- 1H-thieno[2,3-c] pyrazole-5-carbohydrazide (15) were synthesized. These hydrazides (6 and 15) were used as key intermediates in the synthesis of other new pyrazoles 7–12 and thieno[2,3-c]pyrazoles 16–30 respectively. Some of the prepared compounds were screened in vitro for their antibacterial and antifungal activity.
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