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Original Articles

Synthesis of Novel Phosphonopeptides Derived from Pyridylmethylphosphonate Diphenyl Esters

Pages 119-124 | Received 03 May 2001, Published online: 23 Oct 2006
 

Abstract

A series of dipeptides derived from 2-pyridyl- and 3-pyridylmethyl-phosphonic diphenyl esters were synthesized. These dipeptides were obtained in the reaction of the diphenyl 2-pyridylmethyl(amino) phos-phonate or diphenyl 3-pyridylmethyl-(amino)phosphonate with the corresponding Z-blocked aminoacids (alanine, valine, and proline) by the DCC coupling method.

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