Reactivity of 1-Methylisoquinoline. Synthesis of 2-(1-Isoquinolinemethylidene)-1,3,4-Thiadiazole Derivatives

Tayseer A. Abdallah Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt

Hyam A. Abdelhadi Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt

Hamdi M. Hassaneen Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt

Abstract

1-methyl-3,4-dihydro-6,7-dimethoxyisoquinoline reacts with arylisothiocyanates to give the corresponding thioanilides 2 . Treatment of the latter compounds 2 with hydrazonoyl halides 3 and 10 leads to the formation of thiadiazoles 7 and 12 .

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Reactivity of 1-Methylisoquinoline. Synthesis of 2-(1-Isoquinolinemethylidene)-1,3,4-Thiadiazole Derivatives

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Reactivity of 1-Methylisoquinoline. Synthesis of 2-(1-Isoquinolinemethylidene)-1,3,4-Thiadiazole Derivatives

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