Synthesis of Novel [1,2,4]triazolo[3,2-b][2,4,6]benzothiadiazocin-11(5H,10H)-One Derivatives

Abstract

Several [1,2,4]triazolobenzothiadiazocin-11-ones 3 were prepared via ring expansion of [1,2,4]triazolo[3,2-b][2,4]benzothiazepin-10(5H)-ones 1 in presence of sodium azide. The reaction intermediate was isolated and characterized as an aryl isocyanate 2b . A possible pathway for formation of novel triazolobenzothiadiazocin-11-one 3 is described.

Keywords:

• Isocyanate
• Ring Expansion
• Sodium Azide
• Triazolobenzothiadiazocinone
• Triazolobenzothiazepinone
• Tricyclic Heterocycles