One-Pot Synthesis of Thiazoles from Pyridazin-3-hydrazidic Acid Derivatives

Abstract

Several new thiazole derivatives have been synthesized; the reactivity of these compounds toward amines, aldehydes, and hydroxyl amine are reported. New syntheses of pyrimidino[5,4:3,4]pyrazolo[4,3:5,6]pyridazine derivatives also have been achieved.

Keywords:

• Bromoethylcyanoacetate
• Phenylisothio Cyanate
• Pyridazin-3-hydrazidic Acid Derivatives
• Thioglycollic Acid