New Activation Method of Chloroenaminone Quinones for Synthesis of Polynuclear Heterocyclic Systems

Abstract

The chlorine atom of chloroenamineone in the quinonoid compounds 1a-f and 7 was activated by the reaction with benzenesulphonyl chloride to form naphthoquinonid moiety fused with linear or angular heterocyclic systems as carbazoles 2a-c , phenazines 3a , b and 5a-c , phenoxazines 3c phenothiazine 3d , quinoxalinophenazine 6a , quinoxalinophenoxazine 6b , quinoxalinophenthiazine 6c , oxadiazine 8 , thiadiazine 9 , and pyrazole 10 . The mechanism of the latter derivative was discussed. Spectroscopic data of all new products are given. Additionally, the antimicrobial activity of some reported compounds was screened.

Keywords:

• Alkylamino Naphthoquinones
• Heterocyclic Naphthoquinones
• Sulphonylation Reaction