SYNTHESES AND BIOLOGICAL ACTIVITIES OF 1,2,4-TRIAZOLO-[3,4-B][1,3,4]THIADIAZOLE DITHIOPHOSPHATES

Abstract

In this article, we incorporated the organic phosphorus group on to a triazolothiadiazole ring to prepare the title compounds fused 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole heterocyclic compounds. From the results on biological activities, we found that most compounds showed weak activities, and thus the structures need to be further optimized for improved activity.

Keywords:

• Biological activity
• organic phosphorus
• synthesis
• triazolothiadiazole

The authors were very grateful for the National Natural Science Foundation of China (No: 29832050) for the support of this project.