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Original Articles

TRIPHENYLPHOSPHINE-MEDIATED CHEMOSELECTIVE SYNTHESIS OF FUNCTIONALIZED SPIRO-IMIDAZOL-4-ONES

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Pages 1477-1481 | Received 01 Nov 2003, Accepted 01 Jan 2004, Published online: 16 Aug 2010
 

Abstract

Stabilized phosphoranes, obtained from the three-component reaction between dialkyl acetylenedicarboxylates and spiro-hydantoins in the presence of triphenylphosphine, undergo a smooth intramolecular Wittig reaction in boiling toluene to produce functionalized spiro-imidazol-4-ones in good yields.

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