SYNTHESIS AND SEMIEMPIRICAL CALCULATIONS OF THIAZOLIDINONE AND IMIDAZOLIDINONE DERIVATIVES OF α-DIONES

Abstract

The condensation reactions of α-diones with rhodanine and creatinine to give acenaphthylidene, isatylidene and thioisatylidene derivatives, which may act as potential bioactive compounds, are described. The synthesized compounds have been characterized by elemental analysis and spectral studies, as well as by molecular modelling using PCWIN model.

Keywords:

• Acenaphthylidene
• creatinine
• isatylidene and thioisatylidene derivatives
• rhodanine
• semiempirical calculations
• spectral characterization

The authors are thankful to the UGC, New Delhi for financial assistance. A. Jain is thankful to CSIR, New Delhi for NET-JRF scholarship.