ALANINE/CHLOROCHROMIC ACID/SILICA GEL: AN EFFICIENT AND SELECTIVE REAGENT FOR THE OXIDATION OF ORGANIC FUNCTIONAL GROUPS

Abstract

Alanine/chlorochromic acid/silica gel is a new and selective reagent for the efficient oxidation of sulfides, thiols, oximes, and alcohols. Oxidation of sulfides is solvent dependent. In chloroform at room temperature sulfoxides are formed as the major products, while in carbon tetrachloride or under solvent-free conditions solfones are produced in good-to-excellent yields.

Keywords:

• Alcohols
• chlorochromic acid
• oxidation
• oximes
• sulfides
• thiols

Notes

^a Sulfoxides were produced as the final products.

^b Sulfones were produced as the final products.