Dinitrogen Tetroxide Impregnated Charcoal (N₂O₄/Charcoal): Selective Oxidation of Thiols to Disulfides or Thiosulfonates

Selective oxidation of thiols to disulfides (RSSR) was performed by using catalytic amounts of dinitrogen tetroxide/charcoal in chloroform at r.t. while the reaction of thiols with four molar equivalents of the reagent in dichloromethane afforded thiosulfonates (RSO₂SR) with excellent yields.

Keywords:

• Dinitrogen tetroxide
• disulfides
• oxidation
• thiols
• thiosulfonates

Acknowledgments

The authors are thankful to the Shiraz University Research Council for their partial support of this work.

Notes

^a The products were characterized by their comparison with known compounds.^19f

^a The products were characterized by their comparison with known compounds.[19f]