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Original Articles

Asymmetric Synthesis Using Sulfinimines (N-Sulfinyl Imines)

, , , , , , , , , & show all
Pages 1109-1117 | Received 09 Jul 2004, Accepted 05 Oct 2004, Published online: 16 Aug 2006
 

Abstract

Sulfinimine-derived polyfunctionalized chiral building blocks, often prepared in one pot, provide efficient access, with a minimum of chemical manipulation, to enantiopure, multifunctional amine derivatives including piperidines and pyrrolidines.

Acknowledgments

This work was supported through grants from the National Institutes of General Medicinal Sciences (GM 57870 and 51982).

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