Synthesis of Chiral Bis-Thiazolines and Asymmetric Diels–Alder Reactions

Abstract

New chiral ligands, bis-thiazoline derivatives (sulfur analogues of known oxazolines) were prepared from chiral bis-(N-acylamino alcohols) with Lawesson's reagent. Bis-thiazolines thus obtained proved to be useful chiral ligands for metal in asymmetric Diels–Alder reaction.

Keywords:

• Asymmetric catalyst
• bis-(N-acylamino) alcohol
• chiral bis-thiazoline
• Diels–Alder reaction
• Lawesson's reagent