Abstract
A convenient, efficient, and inexpensive procedure for the synthesis of 3-formyl-2-mercaptoquinolines 2a–l has been developed by a simple one-pot reaction of 3-formyl-2-chloroquinolines 1a–l with sodium sulfide and hydrochloric acid in ethanol. The structures of all the synthesized compounds were elucidated on the basis of elemental analyses and IR, 1 H NMR, and mass spectral data.
Acknowledgments
The authors are thankful to V. P. Vaidya, professor and chairman, India, Department of Chemistry and Industrial Chemistry, Kuvempu University, India, for providing laboratory facilities. Authors are also thankful to H. S. Bhojya Naik, head, NMR Research Center, Indian Institute of Science, Bangalore, India, for spectral data.