A Facile and Simple Synthesis of Some New Pyridobenzothiazepine and Pyrimidobenzothiazepine Derivatives

Abstract

2-Amino-3-cyano-4-(2-thienyl)[1,5]benzothiazepine 5 has been synthesized and reacted with some active methylene and nucleophile reagents to yield new pyrido[6,5-b][1,5]benzothiazepine and pyrimido[6,5-b][1,5]benzothiazepine derivatives.

Keywords:

• 1,5-Benzothiazepine
• pyridobenzothiazepine
• pyrimidobenzothiazepine