Abstract
New 4-/5-/6-/7-nitro-N′-(4-aryl-1,3-thiazol-2-yl)-1H-indole-2-carbohydrazides (4a–t) were prepared by treating respective nitroindole thiosemicarbazide with aromatic acylbromides. The newly synthesized compounds were characterized by analytical and spectral data. The compounds were also screened for antifungal and antibacterial activity. Some of the compounds exhibited promising antimicrobial activity.
Acknowledgments
The authors thank the Director, RSIC, Punjab University, Chandigarh, and Prof. Subash Bedi, Director, SAIF, CDRI Luknow for IR, mass, and NMR analysis.
Notes
*All yields are on an isolated basis.