Thiophene-Substituted 1,2,4-Oxadiazoles and Oxadiazines

Abstract

Twenty one new thiophene-substituted 1,2,4-oxadiazol-5(4H)-ones, 1,2,4-oxadiazol-5(4H)-thiones, and 1,2,4-oxadiazin-5(6H)-ones were synthesized by the reaction of thiophene-ring substituted amidoximes with ethyl chloroformate, thiophosgene, and chloroacetylchloride, respectively. Their structure elucidation was performed by means of spectral measurements (IR, NMR, and MS) and physical data.

Keywords:

• Oxadiazine
• oxadiazole
• spectroscopy
• thiadiazole
• thione
• thiophene

Acknowledgments

Abant Izzet Baysal University Research Fund (BAP Grant No. 2003.03.03.184) is gratefully acknowledged for financial assistance.