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Original Articles

One-Pot Multi-Component Approach to the Synthesis of 1,4-Benzothiazines in Aqueous Media

, , &
Pages 13-20 | Received 05 May 2007, Accepted 18 Jun 2007, Published online: 20 Feb 2008
 

Abstract

A new and rapid synthetic strategy for the oxidative cyclocondensation of 2-aminobenzenethiol and 1,3-dicarbonyls has been developed in order to obtain 2,3-disubstituted 1,4-benzothiazines at ambient temperature and in aqueous media. A mechanism is presented to account for the formation of the products.

Acknowledgments

The authors express appreciation to the Shahid Bahonar University of Kerman Faculty Research Committee for its support of this investigation.

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