Abstract
A series of new thiazolidinonyl -4-aryloxymethylcoumarins ( 4a–h ) have been synthesized from 4-Bromomethylcoumarins ( 1a–b ) and 4-aryliminomethyl-phenols ( 2a–d ). Structures of all the new compounds are elucidated by elemental analyses, IR, Citation 1 H NMR, and mass spectral data. All these compounds have been subjected to in-vitro antimicrobial and in-vivo anti-inflammatory screening.
Acknowledgments
We thank the University Scientific Instrumentation Center–Karnatak University Dharwad and Indian Institute of Chemical Technology–Hyderabad, for providing spectral data. K. Shivashankar thanks University Grants Commission, New Delhi, for providing the FIP fellowship.
Notes
**p < 0.01 considered as significant. Superscriptsa - t have not shown significant activity when compared to control.