Synthesis of 3-Substituted (6-[(E)-2-(1-Benzofuran-2-yl)ethenyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles

Abstract

The reaction of (2E)-3-(1-benzofuran-2-yl)-2-propenoic acid with 4-amino-5-R-1,2,4-triazole-3-thioles has been investigated. It has been established, that 6-[(E)-2-(1-benzofuran-2-yl)ethenyl][1,2,4]triazolo[3,4-b][1,3,4] thiadiazole were formed as the result of heterocyclization.

Keywords:

• 1,3,4-thiadiazole
• 1,2,4-triazole
• [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazole
• 4-amino-4H-1,2,4-triazole-3-thiol
• benzofuran derivates
• heterocyclization