The Effects of Reversible Phosphorylation on Peptide and Protein Local Structure

Abstract

Protein phosphorylation is one of the most important forms of protein post-translational modifications. Reversible phosphorylation is related to most physiological and pathological processes. Some of our recent results concerning how phosphorylation participates in modulating protein local structure and adjusting protein properties were summarized in this article.

Keywords:

• Protein phosphorylation
• protein local structure
• protein function

Acknowledgments

The authors appreciate the financial support from the National Natural Science Foundation of China (Nos. 20472041, 20532020, and 20672067), and the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT, IRT0404).