Utility of Hydrazinopiperidinomethanethione in Synthesis of Thiadiazole, Thiadiazine, and Pyrazole Derivatives

Abstract

Hydrazinopiperidinomethanethione 2 was prepared and reacted with active halo compounds, carbon disulfide, phenyliso-thiocyanate, ylidenenitriles, and N,S-acetyls to give thiadiazine 4–7 , thiadiazole 8–10 , and pyrazole 11,13 , 14–17 derivatives, respectively.

Keywords:

• Hydrazinopiperidinomethanethione
• thiadiazine
• thiadiazole

Notes

^aUncorrected;

^bsatisfactory microanalysis obtained C; ± 0.35, H; ± 0.40, N; ± 0.30;

^cmeasured by Nicolet FT-IR 710 spectrophotometer;

^dmeasured by a Varian EM 360 L Spectrometer at 60 MHz using TMS as internal standard and DMSO as a solvent.