Abstract
Dimenthyl(S)-2-hydroxy-3-chloropropylphosphonate is accessible chiron, which was used for the preparation of a number of biologically important enantiomerically pure products, including phospho-GABOB, 2,3-aziridinopropylphosphonate, 2,3-epoxypropylphosphonate, phospho-carnitine, etc., in multigram scale.