High Throughput Screening Under Zinc-Database and Synthesis a Dialkylphosphinic Acid as a Potential Kari Inhibitor

Xing-Hai Liu The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China

Pei-Quan Chen The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China

Wan-Cheng Guo The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China

Su-Hua Wang The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China

Zheng-Ming Li The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China

Abstract

A novel phosphorus derivative was synthesized through HTVS. The title compounds were confirmed by MS, ¹H NMR, ³¹P NMR. The DOCK was also studied.

Keywords:

Acknowledgments

This work was funded by the National Basic Research Program of China (No. 2003CB114406), National Natural Science Foundation Key Project of China (No. 20432010), and The High Performance Computing Project of Tianjin Ministry of Science and Technology of China (No. 043185111-5).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

High Throughput Screening Under Zinc-Database and Synthesis a Dialkylphosphinic Acid as a Potential Kari Inhibitor

Information for

Open access

Opportunities

Help and information

High Throughput Screening Under Zinc-Database and Synthesis a Dialkylphosphinic Acid as a Potential Kari Inhibitor

Abstract

Acknowledgments

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature