Abstract
Several new 2-[bis(2-chloroethyl)amino)]-7-methoxyl-3-alkyl-4-methyl-1,3,2-benzoxazaphosphorin-2-oxides(3a-e) have been synthesized by cyclic condensation of bis(2-chloroethyl)amino phosphoryl dichloride and 2-(1-alkylamino) ethyl-4-methoxylphenol. The title compounds are characterized by NMR, ESI-Q-TOF, and ESI-MS.
Acknowledgments
The authors thank the Chinese National Natural Science Foundation (No. 20472076) and Henan Excellent Youth Grant (No. 0512001400).