Novel Heterocyclic Compounds Containing Sulfur: Synthesis and Insecticidal Activity of (2-Chlorothiazol-5-yl)methyl 2-Phenyliminothiazolidines

Abstract

A series of new (2-chlorothiazol-5-yl)methyl 2-phenyliminothiazolidines were designed and synthesized. All new compounds were characterized by ¹ H NMR and, in some cases, by ¹³ C NMR, IR, and HRMS. They are soluble in most organic solvents, which makes them easier to use. A preliminary bioassay showed that some of the new compounds display insecticidal activity against third-instar larvae of Cx. pipiens pallens at 50 mg/L and moderate insecticidal activity against A. craccivora at 1000 mg/L.

Keywords:

• Insecticidal activity
• 2-phenyliminothiazolidine
• synthesis
• thiazolemethyl

This project was supported by the National Key Project for Basic Research (2003CB114400), the National Natural Science Foundation of China, and the Science and Technology Research Project of the Education Office of Liaoning Province.