Fe(HSO₄)₃ and Fe(HSO₄)₃/DMSO as Efficient, Heterogeneous, and Reusable Catalyst Systems for the Oxidative Coupling of Thiols

Abstract

Fe(HSO₄)₃ has been used as a heterogeneous, efficient, and recyclable catalyst in ethanol for the selective oxidation of thiols to their corresponding disulfides. The same results were obtained under identical conditions using catalytic amounts of Fe(HSO₄)₃ in the presence of DMSO. Different types of aliphatic, aromatic, and heteroaromatic thiols have been used in the reaction, and in all cases the products were obtained in good to excellent yields.

KEYWORDS:

• Disulfide
• DMSO
• Fe(HSO₄)₃
• heterogeneous
• oxidation
• thiol

Notes

^aIsolated yields.

^b–eRefer to the recycling of catalyst in new subsequent runs.

^aIsolated yields.

^bAll reactions were carried out at room temperature.

^cAll reactions were carried out under catalytic amounts of Fe(HSO₄)₃ in the presence of DMSO.