Addition of Hypophosphorous Acid to N,N′-Terephthalylidene-bis[1-(alkoxycarbonyl)alkylamines]

Abstract

The preparation of 1,4-phenylene-bis[1-(alkoxycarbonyl)alkylamino-methanephosphonous acids] by the addition of hypophosphorous acid to terephthalylidene-bis[1-(alkoxycar bonyl)alkylamines] is described. Despite expectations, no chiral assistance of the amino acid ester moiety is observed.

Keywords:

• Amino acid esters
• azomethine bond
• chiral assistance
• chiral terephthalic imines
• hypophosphorous acid

Acknowledgments

Financial support of the Polish Ministry of Science and Higher Education is kindly acknowledged.