A Convenient Synthesis of ω-(2-Aryl-4-oxothiazolidin-3-Yl)alkylphosphonic Acids via In Situ–Generated Arylideneaminoalkylphosphonic Acids

Abstract

ω-(2-Aryl-4-oxothiazolidin-3-yl)alkylphosphonic acids are prepared in an easy workup procedure by the addition of methyl mercaptoacetate to in situ–generated arylideneaminoalkyl phosphonic acids.

Keywords:

• Aminophosphonic acids
• arylideneaminophosphonic acids
• cyclizations
• 4-thiazolidinones

Acknowledgments

This work is dedicated to my mentor, Prof. Romuald Bartnik, University of Łódź, Łódź, Poland, on the occasion of his 70th birthday.This research project was supported by the Faculty of Chemistry, University of Łódź.