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Abstract
Two synthetic routes to phosphonic analogues of indoprofen, a nonsteroidal anti-inflammatory drug, were developed by the cyclization of aniline 2 (method A) and by the Arbuzov reaction of corresponding alkylchloride 3 with triethylphosphite (method B).
Acknowledgments
This work was supported by the STCU grant no. 3558.
Notes
*According to 1Н NMR spectra.