Chemistry of Bis(2-ethynyl-3-thienyl)arene and Related Systems, Part 5: Preparation of an Unsymmetrical 4,4’-Bis(3-thienyl)biphenyl Derivative Containing a 2-[2-(Diphenylphosphino)ethynyl]-3-thienyl Moiety

Abstract

An unsymmetrically substituted 4,4′-bis(3-thienyl)biphenyl derivative of 4-(2-ethynyl-3-thienyl)-4′-(3-thienyl)biphenyl type was prepared, utilizing 4-bromo-4′-(2-iodo-3-thienyl) biphenyl as synthetic intermediate. Reaction of 4-(2-ethynyl-3-thienyl)-4′-(3-thienyl) biphenyl with ethylmagnesium bromide followed by treatment with chlorodiphenylphosphine afforded 4-[2-(2-diphenylphosphinoethynyl)-3-thienyl]-4′-(3-thienyl)biphenyl.

Keywords:

• Artificial enzyme
• artificial molecular architecture
• heterocycles
• oligoarene
• phosphorus ligand

Acknowledgments

Dedicated to Professor Naomichi Furukawa on the occasion of his 70th birthday. This work was supported in part by the Grants-in-Aid for Scientific Research (No. 20550030) from the Ministry of Education, Culture, Sports, Science and Technology.