A Novel and Efficient Synthesis of α-Aminophosphonates by Use of Triphenyl Phosphite in Acetic Acid Media

Abstract

For the first time, α-aminophosphonates were obtained by a simple and efficient one-pot method from the reaction between aldehyde, aniline, and triphenyl phosphite in the presence of acetic acid as a catalyst and solvent at room temperature.

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GRAPHICAL ABSTRACT

Keywords:

• Acetic acid
• α-aminophosphonates
• multicomponent reaction
• triphenyl phosphite

Acknowledgements

The authors sincerely thank the University of Sistan & Baluchestan for providing financial support for this work.

Notes

^aYields refer to the pure isolated products.