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I. Synthesis and Applications in Catalysis

Synthesis of α-Aminophosphine Oxides with Chiral Phosphorus and Carbon Atoms

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Pages 782-784 | Received 07 Jul 2010, Accepted 09 Sep 2010, Published online: 25 Apr 2011
 

Abstract

Lipophilic α-aminophosphine oxides are good extractants for liquid and membrane extraction. Optically active α-aminophosphine oxides, containing chiral centers in their structure, can provide selective means for transfer of stereoisomers through supported liquid membranes. We have developed a method for synthesis of such carrier compounds based on a three-component Kabachnik–Fields reaction.

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