Abstract
A series of new piperazine phosphoramide derivatives of 4-hydroxycoumarin were synthesized through a facile phosphorylating reaction starting from 4-hydroxycoumarin and various phosphorylating agents. The title compounds were characterized by IR, NMR, electrospray ionization-mass spectrometry, and high-resolution mass spectrometry, and their spectroscopic data were further analyzed to feature the related spectroscopic characteristics of the compounds of this class.
GRAPHICAL ABSTRACT
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Acknowledgments
The authors would like to thank the National Natural Science Foundation of China (No. 20472076, 21072178) and Innovation Specialist Projects of Henan Province for their financial support.